Critical Care Reviews Newsletter 313 10th December 2017

The 313th Critical Care Reviews Newsletter brings you the best critical care research and open access articles from across the medical literature over the past seven days.  “The highlights of this week’s issue are two RCTs in out-of-hospital cardiac arrest, investigating inhaled xenon and prehospital cooling respectively, meta analyses on strecritcal care reviewsss ulcer prophylaxis, polymyxin B-immobilized hemoperfusion insepsis, and lung and diaphragmatic ultrasound to predict weaning outcome; plus observational studies on prone positioning in ARDS and hypoxemic respiratory failure in immunocompromised patients. There are also guidelines on bleeding in patients on oral anticoagulants and emergency airway management; and excellent narrative reviews on high-frequency oscillatory ventilation in ARDS , high-flow nasal oxygen and renal replacement therapy for acute brain injury.”

The full copy of newsletter 311 26th November 2017 can be accessed via this link.

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Latest Issue of “Intensive Care Medicine” Volume 43 Number 12

intensive-care-medicineTo access Intensive Care Medicine’s latest issue’s contents page follow this link.

Articles in this issue include “Recommendations for mechanical ventilation of critically ill children from the Paediatric Mechanical Ventilation Consensus Conference (PEMVECC)”, “Terminal weaning or immediate extubation for withdrawing mechanical ventilation in critically ill patients (the ARREVE observational study)” and “The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (≥ 80 years)”.

To access the full text of these articles from the journal’s homepage requires a personal subscription to the journal.  Individual articles can be ordered via the Rotherham NHS Foundation Trust Library and Knowledge Service.  Registered members of the library can make article requests online via this link.

The full text of articles from issues older than one year ago is available via this link to an archive of issues of Intensive Care Medicine.  A Rotherham NHS Athens password is required.  Eligible staff can register for an Athens password via this link.  Please speak to the library staff for more details.

Critical Care Reviews Newsletter 312 3rd December 2017

The 312nd Critical Care Reviews Newsletter brings you the best critical care research and open access articles from across the medical literature over the past seven days.  The highlights of the latest issue are “The highlights of this week’s issue are randomised controlled trials investigating prehospital antibiotics for sepsis & reducing discomfort in critically ill patients; narrative reviews on blood pressure management in acute intracerebral hemorrhage, non-invasive cardiac output monitoring, managing persistent hypoxemia & ventilator-associated pneumonia; as well as commentaries on 10 false beliefs in adult critical care nephrology, medical preprints and five ways to fix statistics.”

The full copy of newsletter 312 3rd December 2017 can be accessed via this link.

Critical Care Reviews Newsletter 311 26th November 2017

The 311th Critical Care Reviews Newsletter brings you the best critical care research and open accescritcal care reviewss articles from across the medical literature over the past seven days.  The highlights of the latest issue are “two randomised controlled trials on high-volume hemofiltration in adult burn patients with septic shock and AKI & the effect of earplugs and eye mask on sleep in critically ill patients; a meta-analysis on renal replacement therapy intensity for AKI; an observational study reporting outcomes after VV ECMO referral for respiratory failure; narrative reviews on the TAME cardiac arrest trial, perioperative cardiac arrest and cardiac output monitoring validation studies; as well as editorials on 48-hour targeted temperature management & iatrogenic hemodilution; plus a commentary on complications of regional citrate anticoagulation.”

The full copy of newsletter 311 26th November 2017 can be accessed via this link.

Current issue of “Intensive and Critical Care Nursing” Volume 43 December 2017

The current issue content page can be accessed via this link.

Articles published in this issue include “Tiered protocol implementation improves treatment of hypoglycaemia in a neurosciences critical care and surgical intensive care unit”, “Prevention of central venous line associated bloodstream infections in adult intintensive and critical care nursingensive care units: A systematic review” and “Going beyond “two-getherness”: Nurse managers’ experiences of working together in a leadership model where more than two share the same chair”

To access the full text of these articles direct from the journal’s homepage requires a personal subscription.  Individual articles can be ordered via the Rotherham NHS Foundation Trust Library and Knowledge Service.  Registered members of the library can make article requests online via this link.

Issues of Intensive and Critical Care Nursing from issue older than one year ago can have their full text accessed via this link.  A Rotherham NHS Athens password is required.  Eligible staff can register for an Athens password via this link.

Critical Care Reviews Newsletter 310 19th November 2017

The 310th Critical Care Reviews Newsletter brings you the best critical care research and open acritcal care reviewsccess articles from across the medical literature over the past seven days.  The highlights of this week’s issue are narrative reviews on airway management in trauma, ischaemic stroke care and critical care echocardiography; commentaries on ICU sedation and fluid administration in the critically ill patient; a guideline on sonography in hypotension and cardiac arrest, and an editorial debate on whether “social media has created emergency medicine celebrities who now influence practice more than published evidence”.

The full copy of newsletter 3095 19th November 2017 can be accessed via this link.

Intensive Care Unit Outcomes Among Patients With Cancer After Palliative Radiation Therapy

This paper by Kruser and colleagues was published in the November issue of the International Journal of Radiation Oncology, Biology and Physics.
Purpose:  To inform goals of care discussions at the time of palliative radiation therapy (RT) consultation, we sought to characterize intensive care unit (ICU) outcomes for patients treated with palliative RT compared to all other patients with metastatic cancer admitted to the ICU.
Methods and materials:  We conducted a retrospective cohort study of patients with metastatic cancer admitted to an ICU in a tertiary medical centre from January 2010 to September 2015. We compared in-hospital mortality between patients who received palliative RT in the 12 months before admission and all other patients with metastatic cancer. We used multivariable logistic regression to evaluate the association between receipt of palliative RT and in-hospital mortality, adjusting for patient characteristics and acute illness severity.
Results:  Among 1424 patients with metastatic cancer, 11.3% (n=161) received palliative RT before ICU admission. In-hospital mortality was 36.7% for palliative RT patients, compared with 16.6% for other patients with metastatic cancer (P<.001). Receipt of palliative RT was associated with increased in-hospital mortality (odds ratio 2.08, 95% confidence interval 1.34-3.21, P=.001), after adjusting for patient characteristics and severity of critical illness. Only 34 patients (21.1%) treated with palliative RT received additional cancer-directed treatment after ICU admission.
Conclusions:  For patients with metastatic cancer, prior treatment with palliative RT is associated with increased in-hospital mortality after ICU admission. Nearly half of patients previously treated with palliative RT either died during hospitalization or were discharged with hospice care, and few received further cancer-directed therapy. Palliative RT referral may represent an opportunity to discuss end-of-life treatment preferences with patients and families.
The article is available on the internet to those who have a personal subscription via this link to the full text.  Library members can order individual articles via the Rotherham NHS Foundation Trust Library and Knowledge Service using the article requests online via this link.