Incidence of Adult Respiratory Distress Syndrome in trauma patients

In trauma patients, acute respiratory distress syndrome (ARDS) is associated with high morbidity and mortality. Changes in diagnostics, management and treatment may have influenced the incidence of ARDS | Journal of Trauma and Acute Care Surgery

Background: The purpose of this manuscript is to evaluate whether there is a difference in the incidence of posttraumatic ARDS 1) over time, 2) attributable to geographic distribution, and 3) related to admitting surgical subspecialities.

Methods: A comprehensive search of articles published in English and German language was conducted using PubMed, MEDLINE, and the ISI Web of Science. Search terms included ARDS, acute respiratory distress syndrome, multiple trauma, polytrauma, and surgery. A meta-regression was performed to analyse differences between several decades of patient recruitment (decade 1: 1981-90; decade 2: 1991-2000; decade 3: 2001-2010), geographic location (North America and Europe), and the type of admitting surgical service (general vs orthopaedic trauma), respectively. Statistical analyses were performed with R (version 3.1.2, metafor package).

Conclusion: The results of this meta-analysis discard the assumption that the following factors have influenced the incidence of postraumatic ARDS: There was neither a change in the incidence over the last decades, nor a geographical difference within western societies, nor associated with the admitting surgical subspeciality.

Full reference: Pfeifer, R. et al. Incidence of Adult Respiratory Distress Syndrome (ARDS) in trauma patients: A systematic review and meta-analysis over a period of three decades. Journal of Trauma and Acute Care Surgery. Post Acceptance: June 6, 2017

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