Noninvasive ventilation with a face mask at preventing is relatively ineffective at preventing endotracheal intubation in patients with acute respiratory distress syndrome (ARDS). Delivery of NIV with a helmet may be a superior strategy for these patients. This RCT compared delivery by helmet vs face mask. Amongst patients with ARDS, treatment with helmet NIV resulted in a significant reduction of intubation rates. There was also a significant reduction in ninety day mortality with helmet NIV.
This trial was published in JAMA volume 315 number 22 14th June 2016. It is available in print in the Healthcare Library on Level D of the hospital. A full abstract and the full text for those with a personal subscription is available via this link.