This randomised controlled trail compared kidney transplant recipients compared a more-intensive belatacept regimen, a less-intensive belatacept regimen, or a cyclosporine regimen over an 84 month period. Seven years after transplantation, patient and graft survival and the mean estimated glomerular filtration rate (eGFR) were significantly higher for both belatacept regimes than for cyclosporine.
The article was published in the New England journal of medicine, vol. 374, no. 4, p. 333-343 (January 28, 2016). The full text can be seen in the Healthcare Library on D Level of Rotherham Hospital or via this link. Please note that most articles in the NEJM are not available freely full text hence the library has a subscription to the physical journal.